|Application ||WB, E|
|Other Accession||NP_741983.2, 23087|
|Calculated MW||56540 Da|
|Other Names||Tripartite motif-containing protein 35, Hemopoietic lineage switch protein 5, TRIM35, HLS5, KIAA1098|
|Format||0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||TRIM35 / MAIR Antibody (N-Term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Reduces FGFR1-dependent tyrosine phosphorylation of PKM, inhibiting PKM-dependent lactate production, glucose metabolism, and cell growth (PubMed:25263439). Involved in the cell death mechanism (By similarity).|
|Cellular Location||Cytoplasm. Nucleus. Note=Found predominantly in cytoplasm with a granular distribution. Found in punctuate nuclear bodies (By similarity).|
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Cloning and characterization of a novel RING-B-box-coiled-coil protein with apoptotic function. Kimura F, Suzu S, Nakamura Y, Nakata Y, Yamada M, Kuwada N, Matsumura T, Yamashita T, Ikeda T, Sato K, Motoyoshi K. J Biol Chem. 2003 Jul 4;278(27):25046-54. PMID: 12692137
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