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INADL / PATJ Antibody (N-Term)

Peptide-affinity purified goat antibody

     
  • IHC - INADL / PATJ Antibody (N-Term) AF2388a
    AF2388a (3.8 µg/ml) staining of paraffin embedded Human Testis. Steamed antigen retrieval with citrate buffer pH 6, AP-staining.
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
IHC, E
Primary Accession Q8NI35
Other Accession NP_795352.2, 10207
Reactivity Human
Predicted Pig, Dog, Cow
Host Goat
Clonality Polyclonal
Concentration 0.5 mg/ml
Isotype IgG
Calculated MW 196368 Da
Additional Information
Gene ID 10207
Other Names InaD-like protein, Inadl protein, hINADL, Pals1-associated tight junction protein, Protein associated to tight junctions, INADL, PATJ
Format 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsINADL / PATJ Antibody (N-Term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name INADL
Synonyms PATJ
Function Scaffolding protein that may bring different proteins into adjacent positions at the cell membrane. May regulate protein targeting, cell polarity and integrity of tight junctions. May regulate the surface expression and/or function of ASIC3 in sensory neurons.
Cellular Location Membrane. Cell junction, tight junction. Apical cell membrane. Cytoplasm, perinuclear region Note=Localized in the paranodal region of myelinating Schwann cells (By similarity). Membrane-associated. Localizes to tight junctions in epithelial cells. Also found at the apical plasma membrane.
Tissue Location Expressed in bladder, testis, ovary, small intestine, colon, heart, skeletal muscle, pancreas and cerebellum in the brain.
Research Areas
Citations (0)

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References

Molecular characterization of a novel human PDZ domain protein with homology to INAD from Drosophila melanogaster. Philipp S, Flockerzi V. FEBS Lett. 1997 Aug 18;413(2):243-8. PMID: 9280290

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$ 335.00
Cat# AF2388a
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