AKAP6 Antibody (N-Term)
Peptide-affinity purified goat antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, E |
---|---|
Primary Accession | Q13023 |
Other Accession | NP_004265.3, 9472, 238161 (mouse), 64553 (rat) |
Reactivity | Mouse |
Predicted | Human, Rat, Pig, Dog, Cow |
Host | Goat |
Clonality | Polyclonal |
Concentration | 0.5 mg/ml |
Isotype | IgG |
Calculated MW | 256720 Da |
Gene ID | 9472 |
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Other Names | A-kinase anchor protein 6, AKAP-6, A-kinase anchor protein 100 kDa, AKAP 100, Protein kinase A-anchoring protein 6, PRKA6, mAKAP, AKAP6, AKAP100, KIAA0311 |
Format | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | AKAP6 Antibody (N-Term) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | AKAP6 |
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Synonyms | AKAP100, KIAA0311 |
Function | Binds to type II regulatory subunits of protein kinase A and anchors/targets them to the nuclear membrane or sarcoplasmic reticulum. May act as an adapter for assembling multiprotein complexes. |
Cellular Location | Sarcoplasmic reticulum. Nucleus membrane. Note=In heart muscle. Participation of multiple targeting signals allow correct intracellular targeting. These may be repeated motifs rich in basic and hydrophobic amino acids, palmitoylated/myristoylated motifs or alternatively splice targeting sequences |
Tissue Location | Highly expressed in cardiac and skeletal muscle, followed by brain |
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Provided below are standard protocols that you may find useful for product applications.
References
Cloning and characterization of A-kinase anchor protein 100 (AKAP100). A protein that targets A-kinase to the sarcoplasmic reticulum. McCartney S, Little BM, Langeberg LK, Scott JD. J Biol Chem. 1995 Apr 21;270(16):9327-33. PMID: 7721854
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