|Application ||WB, E|
|Other Accession||NP_004265.3, 9472, 238161 (mouse), 64553 (rat)|
|Predicted||Human, Rat, Pig, Dog, Cow|
|Calculated MW||256720 Da|
|Other Names||A-kinase anchor protein 6, AKAP-6, A-kinase anchor protein 100 kDa, AKAP 100, Protein kinase A-anchoring protein 6, PRKA6, mAKAP, AKAP6, AKAP100, KIAA0311|
|Format||0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||AKAP6 Antibody (N-Term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Binds to type II regulatory subunits of protein kinase A and anchors/targets them to the nuclear membrane or sarcoplasmic reticulum. May act as an adapter for assembling multiprotein complexes.|
|Cellular Location||Sarcoplasmic reticulum. Nucleus membrane. Note=In heart muscle. Participation of multiple targeting signals allow correct intracellular targeting. These may be repeated motifs rich in basic and hydrophobic amino acids, palmitoylated/myristoylated motifs or alternatively splice targeting sequences|
|Tissue Location||Highly expressed in cardiac and skeletal muscle, followed by brain|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Cloning and characterization of A-kinase anchor protein 100 (AKAP100). A protein that targets A-kinase to the sarcoplasmic reticulum. McCartney S, Little BM, Langeberg LK, Scott JD. J Biol Chem. 1995 Apr 21;270(16):9327-33. PMID: 7721854
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