PRL1 / PTP4A1 Antibody (C-Term)
Peptide-affinity purified goat antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, E |
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Primary Accession | Q93096 |
Other Accession | NP_003454.1, 7803 |
Reactivity | Human |
Predicted | Mouse, Rat, Dog |
Host | Goat |
Clonality | Polyclonal |
Concentration | 0.5 mg/ml |
Isotype | IgG |
Calculated MW | 19815 Da |
Gene ID | 7803 |
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Other Names | Protein tyrosine phosphatase type IVA 1, 3.1.3.48, PTP(CAAXI), Protein-tyrosine phosphatase 4a1, Protein-tyrosine phosphatase of regenerating liver 1, PRL-1, PTP4A1, PRL1, PTPCAAX1 |
Format | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | PRL1 / PTP4A1 Antibody (C-Term) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | PTP4A1 |
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Synonyms | PRL1, PTPCAAX1 |
Function | Protein tyrosine phosphatase which stimulates progression from G1 into S phase during mitosis. May play a role in the development and maintenance of differentiating epithelial tissues. Enhances cell proliferation, cell motility and invasive activity, and promotes cancer metastasis. |
Cellular Location | Cell membrane; Lipid-anchor. Early endosome. Endoplasmic reticulum. Cytoplasm Cytoplasm, cytoskeleton, spindle. Nucleus {ECO:0000250|UniProtKB:Q78EG7}. Note=And mitotic spindle |
Tissue Location | Expressed in bone marrow, lymph nodes, T lymphocytes, spleen, thymus and tonsil. Overexpressed in tumor cell lines. |
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Provided below are standard protocols that you may find useful for product applications.
References
The gene encoding human nuclear protein tyrosine phosphatase, PRL-1. Cloning, chromosomal localization, and identification of an intron enhancer. Peng Y, Genin A, Spinner NB, Diamond RH, Taub R. J Biol Chem. 1998 Jul 3;273(27):17286-95. PMID: 9642300
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