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Rhophilin 2 (Internal) Antibody (internal region)

Peptide-affinity purified goat antibody

  • IHC - Rhophilin 2 (Internal) Antibody (internal region) AF2447a
    AF2447a (5 µg/ml) staining of paraffin embedded Human Kidney. Steamed antigen retrieval with citrate buffer pH 6, AP-staining.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q8IUC4
Other Accession NP_149094.3, 85415
Reactivity Human
Predicted Mouse, Rat, Cow
Host Goat
Clonality Polyclonal
Concentration 0.5 mg/ml
Isotype IgG
Calculated MW 76993 Da
Additional Information
Gene ID 85415
Other Names Rhophilin-2, 76 kDa RhoB effector protein, GTP-Rho-binding protein 2, p76RBE, RHPN2
Format 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsRhophilin 2 (Internal) Antibody (internal region) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name RHPN2
Function Binds specifically to GTP-Rho. May function in a Rho pathway to limit stress fiber formation and/or increase the turnover of F-actin structures in the absence of high levels of RhoA activity.
Cellular Location Cytoplasm, perinuclear region
Tissue Location Widely expressed. Highly expressed in prostate, trachea, stomach, colon, thyroid and pancreas. Expressed at lower level in brain, spinal cord, kidney, placenta and liver
Research Areas
Citations (0)

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The RhoA-binding protein, rhophilin-2, regulates actin cytoskeleton organization. Peck JW, Oberst M, Bouker KB, Bowden E, Burbelo PD. J Biol Chem. 2002 Nov 15;277(46):43924-32. PMID: 12221077

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$ 325.00
Cat# AF2447a
(40 western blots)
Availability: 7-10 days
Bulk Size
Seasonal Special on Bulk Order
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