|Application ||IHC, E|
|Other Accession||NP_002155.1, 3620|
|Predicted||Human, Mouse, Rat, Dog|
|Calculated MW||45326 Da|
|Other Names||Indoleamine 2, 3-dioxygenase 1, IDO-1, 22.214.171.124, Indoleamine-pyrrole 2, 3-dioxygenase, IDO1, IDO, INDO|
|Format||0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||INDO / IDO Antibody (internal region) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Catalyzes the cleavage of the pyrrol ring of tryptophan and incorporates both atoms of a molecule of oxygen.|
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Provided below are standard protocols that you may find useful for product applications.
GCN2 kinase in T cells mediates proliferative arrest and anergy induction in response to indoleamine 2,3-dioxygenase. Munn DH, Sharma MD, Baban B, Harding HP, Zhang Y, Ron D, Mellor AL. Immunity. 2005 May;22(5):633-42. PMID: 15894280
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