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LNX1 Antibody (internal region)

Peptide-affinity purified goat antibody

Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q8TBB1
Other Accession NP_116011.1, 84708
Predicted Human
Host Goat
Clonality Polyclonal
Concentration 0.5 mg/ml
Isotype IgG
Calculated MW 80629 Da
Additional Information
Gene ID 84708
Other Names E3 ubiquitin-protein ligase LNX, 6.3.2.-, Ligand of Numb-protein X 1, Numb-binding protein 1, PDZ domain-containing RING finger protein 2, LNX1, LNX, PDZRN2
Format 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsLNX1 Antibody (internal region) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name LNX1
Synonyms LNX, PDZRN2
Function E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of NUMB. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Mediates ubiquitination of isoform p66 and isoform p72 of NUMB, but not that of isoform p71 or isoform p65 (By similarity).
Cellular Location Cytoplasm.
Tissue Location Expressed in heart, placenta, kidney, pancreas and brain.
Research Areas
Citations (0)

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Characterization of human LNX, a novel ligand of Numb protein X that is downregulated in human gliomas. Chen J, Xu J, Zhao W, Hu G, Cheng H, Kang Y, Xie Y, Lu Y. Int J Biochem Cell Biol. 2005 Nov;37(11):2273-83. Epub 2005 Apr 11. PMID: 16002321

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$ 325.00
Cat# AF2581a
(40 western blots)
Availability: 7-10 days
Bulk Size
Seasonal Special on Bulk Order
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