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UNC45B Antibody (internal region)

Peptide-affinity purified goat antibody

  • WB - UNC45B Antibody (internal region) AF2594a
    AF2594a (0.3 µg/ml) staining of Human Skeletal Muscle lysate (35 µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q8IWX7
Other Accession NP_775259.1, NP_001028748.1, 146862, 217012 (mouse), 303373 (rat)
Reactivity Human
Predicted Mouse, Rat, Dog
Host Goat
Clonality Polyclonal
Concentration 0.5 mg/ml
Isotype IgG
Calculated MW 103733 Da
Additional Information
Gene ID 146862
Other Names Protein unc-45 homolog B, Unc-45B, SMUNC45, UNC45B, CMYA4, UNC45
Format 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsUNC45B Antibody (internal region) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name UNC45B
Synonyms CMYA4, UNC45
Function Acts as a co-chaperone for HSP90 and is required for proper folding of the myosin motor domain. Plays a role in sarcomere formation during muscle cell development (By similarity).
Cellular Location Cytoplasm, cytosol.
Research Areas
Citations (0)

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This antibody is expected to recognise both reported isoforms (NP_775259.1and NP_001028748.1).


The UNC-45 chaperone mediates sarcomere assembly through myosin degradation in Caenorhabditis elegans. Landsverk ML, Li S, Hutagalung AH, Najafov A, Hoppe T, Barral JM, Epstein HF. J Cell Biol. 2007 Apr 23;177(2):205-10. Epub 2007 Apr 16. PMID: 17438072

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$ 325.00
Cat# AF2594a
(40 western blots)
Availability: 7-10 days
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