|Application ||WB, E|
|Other Accession||NP_679211.1, NP_001157753.1, 10758|
|Calculated MW||64666 Da|
|Other Names||Adapter protein CIKS, Connection to IKK and SAPK/JNK, Nuclear factor NF-kappa-B activator 1, ACT1, TRAF3-interacting protein 2, TRAF3IP2, C6orf2, C6orf4, C6orf5, C6orf6|
|Format||0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||TRAF3IP2 Antibody (C or N-Term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Synonyms||C6orf2, C6orf4, C6orf5, C6orf6|
|Function||Could be involved in the activation of both NF-kappa-B via a NF-kappa-B inhibitor kinase (IKK)-dependent mechanism and stress-activated protein kinase (SAPK)/JNK.|
|Tissue Location||Widely expressed.|
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Provided below are standard protocols that you may find useful for product applications.
This antibody is expected to recognise both reported isoforms (NP_671733.1 and NP_679211.1).
The adaptor Act1 is required for interleukin 17-dependent signaling associated with autoimmune and inflammatory disease. Qian Y, Liu C, Hartupee J, Altuntas CZ, Gulen MF, Jane-Wit D, Xiao J, Lu Y, Giltiay N, Liu J, Kordula T, Zhang QW, Vallance B, Swaidani S, Aronica M, Tuohy VK, Hamilton T, Li X. Nat Immunol. 2007 Mar;8(3):247-56. Epub 2007 Feb 4. PMID: 17277779
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