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KCC4 / SLC12A7 Antibody (internal region)

Peptide-affinity purified goat antibody

Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9Y666
Other Accession NP_006589.2, 10723, 20499 (mouse)
Predicted Human, Mouse
Host Goat
Clonality Polyclonal
Concentration 0.5 mg/ml
Isotype IgG
Calculated MW 119106 Da
Additional Information
Gene ID 10723
Other Names Solute carrier family 12 member 7, Electroneutral potassium-chloride cotransporter 4, K-Cl cotransporter 4, SLC12A7, KCC4
Format 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsKCC4 / SLC12A7 Antibody (internal region) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name SLC12A7
Synonyms KCC4
Function Mediates electroneutral potassium-chloride cotransport when activated by cell swelling. May mediate K(+) uptake into Deiters' cells in the cochlea and contribute to K(+) recycling in the inner ear. Important for the survival of cochlear outer and inner hair cells and the maintenance of the organ of Corti. May be required for basolateral Cl(-) extrusion in the kidney and contribute to renal acidification (By similarity).
Cellular Location Cell membrane; Multi-pass membrane protein.
Tissue Location Detected in muscle, brain, lung, heart and kidney
Research Areas
Citations (0)

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Homooligomeric and heterooligomeric associations between K+-Cl- cotransporter isoforms and between K+-Cl- and Na+-K+-Cl- cotransporters. Simard CF, Bergeron MJ, Frenette-Cotton R, Carpentier GA, Pelchat ME, Caron L, Isenring P. J Biol Chem. 2007 Jun 22;282(25):18083-93. Epub 2007 Apr 26. PMID: 17462999

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$ 325.00
Cat# AF2635a
(40 western blots)
Availability: 7-10 days
Bulk Size
Seasonal Special on Bulk Order
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