|Application ||WB, E|
|Other Accession||NP_004272.2, 9531|
|Calculated MW||61595 Da|
|Other Names||BAG family molecular chaperone regulator 3, BAG-3, Bcl-2-associated athanogene 3, Bcl-2-binding protein Bis, Docking protein CAIR-1, BAG3, BIS|
|Format||0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||BAG3 Antibody (internal region) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Inhibits the chaperone activity of HSP70/HSC70 by promoting substrate release. Has anti-apoptotic activity.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
BAG3 deficiency results in fulminant myopathy and early lethality. Homma S, Iwasaki M, Shelton GD, Engvall E, Reed JC, Takayama S. Am J Pathol. 2006 Sep;169(3):761-73. PMID: 16936253
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