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>   home   >   Products   >   Primary Antibodies   >   Antibody Collections   >   Goat Antibodies   >   FYB Antibody (internal region)   

FYB Antibody (internal region)

Peptide-affinity purified goat antibody

  • WB - FYB Antibody (internal region) AF2680a
    AF2680a (0.2 µg/ml) staining of MOLT4 lysate (35 µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession O15117
Other Accession NP_001456.3, NP_955367.1, NP_001230022.1, 2533
Reactivity Human
Predicted Dog, Cow
Host Goat
Clonality Polyclonal
Concentration 0.5 mg/ml
Isotype IgG
Calculated MW 85387 Da
Additional Information
Gene ID 2533
Other Names FYN-binding protein, Adhesion and degranulation promoting adaptor protein, ADAP, FYB-120/130, p120/p130, FYN-T-binding protein, SLAP-130, SLP-76-associated phosphoprotein, FYB, SLAP130
Format 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsFYB Antibody (internal region) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name FYB
Synonyms SLAP130
Function Acts as an adapter protein of the FYN and LCP2 signaling cascades in T-cells. Modulates the expression of interleukin-2 (IL-2). Involved in platelet activation. Prevents the degradation of SKAP1 and SKAP2. May play a role in linking T-cell signaling to remodeling of the actin cytoskeleton.
Cellular Location Cytoplasm. Nucleus
Tissue Location Expressed in hematopoietic tissues such as myeloid and T-cells, spleen and thymus. Not expressed in B-cells, nor in non-lymphoid tissues
Research Areas
Citations (0)

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This antibody is expected to recognise all reported isoforms (NP_001456.3; NP_955367.1; NP_001230022.1).


Regulation of NF-kappaB activation in T cells via association of the adapter proteins ADAP and CARMA1. Medeiros RB, Burbach BJ, Mueller KL, Srivastava R, Moon JJ, Highfill S, Peterson EJ, Shimizu Y. Science. 2007 May 4;316(5825):754-8. PMID: 17478723

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$ 325.00
Cat# AF2680a
(40 western blots)
Availability: 7-10 days
Bulk Size
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