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AADACL1 Antibody (C-Term)

Peptide-affinity purified goat antibody

Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q6PIU2
Other Accession NP_065843.3, 57552, 320024 (mouse)
Predicted Human, Mouse, Dog
Host Goat
Clonality Polyclonal
Concentration 0.5 mg/ml
Isotype IgG
Calculated MW 45808 Da
Additional Information
Gene ID 57552
Other Names Neutral cholesterol ester hydrolase 1, NCEH, 3.1.1.-, Arylacetamide deacetylase-like 1, NCEH1, AADACL1, KIAA1363
Format 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsAADACL1 Antibody (C-Term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name NCEH1
Synonyms AADACL1, KIAA1363
Function Hydrolyzes 2-acetyl monoalkylglycerol ether, the penultimate precursor of the pathway for de novo synthesis of platelet-activating factor. May be responsible for cholesterol ester hydrolysis in macrophages, thereby contributing to the development of atherosclerosis. Also involved in organ detoxification by hydrolyzing exogenous organophosphorus compounds. May contribute to cancer pathogenesis by promoting tumor cell migration.
Cellular Location Membrane; Single-pass type II membrane protein. Microsome
Tissue Location Expressed in monocyte-derived macrophages. Up- regulated in invasive melanoma and breast carcinoma cell lines
Research Areas
Citations (0)

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An enzyme that regulates ether lipid signaling pathways in cancer annotated by multidimensional profiling. Chiang KP, Niessen S, Saghatelian A, Cravatt BF. Chem Biol. 2006 Oct;13(10):1041-50. PMID: 17052608

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$ 325.00
Cat# AF2704a
(40 western blots)
Availability: 7-10 days
Bulk Size
Seasonal Special on Bulk Order
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