|Other Accession||NP_004576.2, 5920|
|Calculated MW||18179 Da|
|Other Names||Retinoic acid receptor responder protein 3, 3.1.1.-, HRAS-like suppressor 4, HRSL4, RAR-responsive protein TIG3, Retinoid-inducible gene 1 protein, Tazarotene-induced gene 3 protein, RARRES3, RIG1, TIG3|
|Format||0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||RIG1 / RARRES3 (aa 124 to 136) Antibody (internal region) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Exhibits PLA1/2 activity, catalyzing the calcium- independent hydrolysis of acyl groups in various phosphotidylcholines (PC) and phosphatidylethanolamine (PE). For most substrates, PLA1 activity is much higher than PLA2 activity. N- and O-acylation activity is hardly detectable.|
|Cellular Location||Membrane; Single-pass membrane protein|
|Tissue Location||Widely expressed.|
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Provided below are standard protocols that you may find useful for product applications.
RIG1 suppresses Ras activation and induces cellular apoptosis at the Golgi apparatus. Tsai FM, Shyu RY, Jiang SY. Cell Signal. 2007 May;19(5):989-99. Epub 2006 Nov 23. PMID: 17196792
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