|Other Accession||NP_004576.2, 5920|
|Calculated MW||18179 Da|
|Other Names||Retinoic acid receptor responder protein 3, 3.1.1.-, HRAS-like suppressor 4, HRSL4, RAR-responsive protein TIG3, Retinoid-inducible gene 1 protein, Tazarotene-induced gene 3 protein, RARRES3, RIG1, TIG3|
|Format||0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||RIG1 / RARRES3 (aa 124 to 136) Antibody (internal region) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Exhibits PLA1/2 activity, catalyzing the calcium- independent hydrolysis of acyl groups in various phosphotidylcholines (PC) and phosphatidylethanolamine (PE). For most substrates, PLA1 activity is much higher than PLA2 activity. N- and O-acylation activity is hardly detectable.|
|Cellular Location||Membrane; Single-pass membrane protein|
|Tissue Location||Widely expressed.|
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RIG1 suppresses Ras activation and induces cellular apoptosis at the Golgi apparatus. Tsai FM, Shyu RY, Jiang SY. Cell Signal. 2007 May;19(5):989-99. Epub 2006 Nov 23. PMID: 17196792
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