|Application ||IHC, E|
|Other Accession||NP_060348.1, 54979|
|Calculated MW||17394 Da|
|Other Names||HRAS-like suppressor 2, 2.3.1.-, 3.1.1.-, HRASLS2|
|Format||0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||HRASLS2 Antibody (internal region) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Exhibits PLA1/2 activity, catalyzing the calcium- independent hydrolysis of acyl groups in various phosphatidylcholines (PC) and phosphatidylethanolamine (PE). For most substrates, PLA1 activity is much higher than PLA2 activity. Catalyzes N-acylation of PE using both sn-1 and sn-2 palmitoyl groups of PC as acyl donor. Also catalyzes O-acylation converting lyso-PC into PC.|
|Cellular Location||Cytoplasm. Membrane; Single-pass membrane protein. Note=Exhibits a granular pattern in the cytoplasm with preferential perinuclear localization|
|Tissue Location||Expressed in liver, kidney, small intestine testis and colon (PubMed:19615464). Undetectable in testis, placenta, salivary gland and fetal brain (PubMed:18163183)|
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Provided below are standard protocols that you may find useful for product applications.
This design was based on provisional sequence data.
Cloning and functional characterization of the HRASLS2 gene. Shyu RY, Hsieh YC, Tsai FM, Wu CC, Jiang SY. Amino Acids. 2008 Jun;35(1):129-37. PMID: 18163183
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