|Other Accession||NP_004787.2, 9369, 18191 (mouse)|
|Predicted||Human, Mouse, Pig, Dog|
|Calculated MW||180599 Da|
|Other Names||Neurexin-3, Neurexin III-alpha, Neurexin-3-alpha, NRXN3, C14orf60, KIAA0743|
|Format||0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||Neurexin 3 / NRXN3 Antibody (internal region) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Neuronal cell surface protein that may be involved in cell recognition and cell adhesion. May mediate intracellular signaling.|
|Cellular Location||Membrane; Single-pass type I membrane protein|
|Tissue Location||Expressed in the blood vessel walls (at protein level). Highly expressed in brain, lung, and pancreas; a lower level of expression is detectable in heart, placenta, liver, and kidney, whereas no expression can be observed in skeletal muscle. Isoform 4a is heart-specific|
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Provided below are standard protocols that you may find useful for product applications.
This antibody is expected to recognize the reported isoform 1 (NP_004787.2).
Candidate gene/loci studies in cleft lip/palate and dental anomalies finds novel susceptibility genes for clefts.
susceptibility genes for clefts. Vieira AR, McHenry TG, Daack-Hirsch S, Murray JC, Marazita ML. Genet Med. 2008 Sep;10(9):668-74. PMID: 18978678
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