TFAP2D (aa70-82) Antibody (internal region)
Peptide-affinity purified goat antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| E |
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Primary Accession | Q7Z6R9 |
Other Accession | NP_758438.2, 83741, 226896 (mouse) |
Predicted | Human, Mouse |
Host | Goat |
Clonality | Polyclonal |
Concentration | 0.5 mg/ml |
Isotype | IgG |
Calculated MW | 49578 Da |
Gene ID | 83741 |
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Other Names | Transcription factor AP-2-delta, AP2-delta, Activating enhancer-binding protein 2-delta, Transcription factor AP-2-beta-like 1, TFAP2D (HGNC:15581) |
Format | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | TFAP2D (aa70-82) Antibody (internal region) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | TFAP2D (HGNC:15581) |
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Function | Sequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes. AP-2 factors bind to the consensus sequence 5'-GCCNNNGGC-3' and activate genes involved in a large spectrum of important biological functions including proper eye, face, body wall, limb and neural tube development. They also suppress a number of genes including MCAM/MUC18, C/EBP alpha and MYC (By similarity). |
Cellular Location | Nucleus. |
Tissue Location | Highly expressed in brain, placenta, skeletal muscle, thymus, small intestine, and prostate, and expressed at lower levels in leukocyte, spleen, testis, ovary and colon. Barely detectable in heart, kidney, liver, lung or pancreas |
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Provided below are standard protocols that you may find useful for product applications.
References
Regulation of integrin alpha10 expression in chondrocytes by the transcription factors AP-2epsilon and Ets-1 Wenke AK, Rothhammer T, Moser M, Bosserhoff AK Biochem Biophys Res Commun. 2006 Jun 23;345(1):495-501. Epub 2006 May 2 PMID: 16684505
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