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KALRN Antibody (N-Term)

Peptide-affinity purified goat antibody

Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession O60229
Other Accession NP_001019831.2, NP_003938.1, NP_008995.2, 8997, 545156 (mouse), 84009 (rat)
Predicted Human, Mouse, Rat, Cow
Host Goat
Clonality Polyclonal
Concentration 0.5 mg/ml
Isotype IgG
Calculated MW 340174 Da
Additional Information
Gene ID 8997
Other Names Kalirin,, Huntingtin-associated protein-interacting protein, Protein Duo, Serine/threonine-protein kinase with Dbl- and pleckstrin homology domain, KALRN, DUET, DUO, HAPIP, TRAD
Format 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsKALRN Antibody (N-Term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Function Promotes the exchange of GDP by GTP. Activates specific Rho GTPase family members, thereby inducing various signaling mechanisms that regulate neuronal shape, growth, and plasticity, through their effects on the actin cytoskeleton. Induces lamellipodia independent of its GEF activity.
Cellular Location Cytoplasm. Cytoplasm, cytoskeleton Note=Associated with the cytoskeleton
Tissue Location Isoform 2 is brain specific. Highly expressed in cerebral cortex, putamen, amygdala, hippocampus and caudate nucleus. Weakly expressed in brain stem and cerebellum. Isoform 4 is expressed in skeletal muscle.
Research Areas
Citations (0)

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This antibody is expected to recognize reported isoforms NP_001019831.2 and NP_003938.1.


Kalirin-7 controls activity-dependent structural and functional plasticity of dendritic spines. Xie Z, Srivastava DP, Photowala H, Kai L, Cahill ME, Woolfrey KM, Shum CY, Surmeier DJ, Penzes P. Neuron. 2007 Nov 21;56(4):640-56. PMID: 18031682

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$ 325.00
Cat# AF2867a
(40 western blots)
Availability: 7-10 days
Bulk Size
Seasonal Special on Bulk Order
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