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FBXO32 Antibody (internal region)

Peptide-affinity purified goat antibody

  • WB - FBXO32 Antibody (internal region) AF2885a
    AF2885a (1 µg/ml) staining of Human Skeletal Muscle lysate (35 µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q969P5
Other Accession NP_478136.1, 114907, 67731 (mouse), 171043 (rat)
Reactivity Human, Mouse
Predicted Rat, Pig, Cow
Host Goat
Clonality Polyclonal
Concentration 0.5 mg/ml
Isotype IgG
Calculated MW 41637 Da
Additional Information
Gene ID 114907
Other Names F-box only protein 32, Atrogin-1, Muscle atrophy F-box protein, MAFbx, FBXO32
Format 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsFBXO32 Antibody (internal region) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name FBXO32
Function Substrate recognition component of a SCF (SKP1-CUL1-F- box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Probably recognizes and binds to phosphorylated target proteins during skeletal muscle atrophy. Recognizes TERF1.
Cellular Location Cytoplasm. Nucleus. Note=Shuttles between Cytoplasm and the nucleus
Tissue Location Specifically expressed in cardiac and skeletal muscle
Research Areas
Citations (0)

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This antibody is expected to recognize reported isoform 1 (NP_478136.1).


The muscle-specific ubiquitin ligase atrogin-1/MAFbx mediates statin-induced muscle toxicity. Hanai J, Cao P, Tanksale P, Imamura S, Koshimizu E, Zhao J, Kishi S, Yamashita M, Phillips PS, Sukhatme VP, Lecker SH. J Clin Invest. 2007 Dec;117(12):3940-51. PMID: 17992259

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$ 325.00
Cat# AF2885a
(40 western blots)
Availability: 7-10 days
Bulk Size
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