TEX11 Antibody (internal region)
Peptide-affinity purified goat antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| E |
---|---|
Primary Accession | Q8IYF3 |
Other Accession | NP_001003811.1, NP_112566.2, 56159 |
Predicted | Human |
Host | Goat |
Clonality | Polyclonal |
Concentration | 0.5 mg/ml |
Isotype | IgG |
Calculated MW | 107889 Da |
Gene ID | 56159 |
---|---|
Other Names | Testis-expressed sequence 11 protein, TEX11 |
Format | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | TEX11 Antibody (internal region) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | TEX11 |
---|---|
Synonyms | ZIP4 {ECO:0000250|UniProtKB:Q14AT2} |
Function | Regulator of crossing-over during meiosis. Involved in initiation and/or maintenance of chromosome synapsis and formation of crossovers. |
Cellular Location | Chromosome {ECO:0000250|UniProtKB:Q14AT2}. Note=Forms arrays of discrete foci along synaptonemal complexes in spermatocytes and fetal oocytes. {ECO:0000250|UniProtKB:Q14AT2} |
Tissue Location | Testis-specific. Not expressed in adult ovaries. |
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Provided below are standard protocols that you may find useful for product applications.
Background
This antibody is expected to recognize both reported isoforms (NP_112566.2; NP_001003811.1).
References
Meiotic failure in male mice lacking an X-linked factor. Yang F, Gell K, van der Heijden GW, Eckardt S, Leu NA, Page DC, Benavente R, Her C, Höög C, McLaughlin KJ, Wang PJ. Genes Dev. 2008 Mar 22 (5): 682-91. PMID: 18316482
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