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UNC5C Antibody (internal region)

Peptide-affinity purified goat antibody

  • IF - UNC5C  Antibody (internal region) AF2932a
    AF2932a (50ug/ml) staining of islets in Mouse Pancreas. Citrate antigen retrieval. Detected by immunofluorescence.
  • IHC - UNC5C  Antibody (internal region) AF2932a
    AF2932a (3.8 µg/ml) staining of paraffin embedded Human Cerebral Cortex. Steamed antigen retrieval with citrate buffer pH 6, AP-staining.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession O95185
Other Accession NP_003719.2, 8633, 22253 (mouse)
Reactivity Human, Mouse
Predicted Dog
Host Goat
Clonality Polyclonal
Concentration 0.5 mg/ml
Isotype IgG
Calculated MW 103146 Da
Additional Information
Gene ID 8633
Other Names Netrin receptor UNC5C, Protein unc-5 homolog 3, Protein unc-5 homolog C, UNC5C, UNC5H3
Format 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsUNC5C Antibody (internal region) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name UNC5C
Synonyms UNC5H3
Function Receptor for netrin required for axon guidance. Mediates axon repulsion of neuronal growth cones in the developing nervous system upon ligand binding. Axon repulsion in growth cones may be caused by its association with DCC that may trigger signaling for repulsion. Also involved in corticospinal tract axon guidances independently of DCC. It also acts as a dependence receptor required for apoptosis induction when not associated with netrin ligand (By similarity).
Cellular Location Membrane; Single-pass type I membrane protein
Tissue Location Mainly expressed in brain. Also expressed in kidney. Not expressed in developing or adult lung
Research Areas
Citations (0)

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Epigenetic and genetic alterations in Netrin-1 receptors UNC5C and DCC in human colon cancer. Shin SK, Nagasaka T, Jung BH, Matsubara N, Kim WH, Carethers JM, Boland CR, Goel A. Gastroenterology 2007 Dec 133 (6): 1849-57. PMID: 18054557

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$ 325.00
Cat# AF2932a
(40 western blots)
Availability: 7-10 days
Bulk Size
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