|Other Accession||NP_005948.3, 4524|
|Calculated MW||74597 Da|
|Other Names||Methylenetetrahydrofolate reductase, 188.8.131.52, MTHFR|
|Format||0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||MTHFR Antibody (C-Term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Catalyzes the conversion of 5,10- methylenetetrahydrofolate to 5-methyltetrahydrofolate, a co- substrate for homocysteine remethylation to methionine.|
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Functional polymorphisms in folate metabolism genes influence the risk of meningioma and glioma. Bethke L, Webb E, Murray A, Schoemaker M, Feychting M, Lönn S, Ahlbom A, Malmer B, Henriksson R, Auvinen A, Kiuru A, Salminen T, Johansen C, Christensen HC, Muir K, McKinney P, Hepworth S, Dimitropoulou P, Lophatananon A, Swerdlow A, Houlston R. Cancer Epidemiol. Biomarkers Prev. 2008 May 17 (5): 1195-202. PMID: 18483342
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