|Application ||WB, E|
|Other Accession||NP_001124.1, 173, 75547 (mouse), 293024 (rat)|
|Predicted||Mouse, Rat, Dog, Cow|
|Calculated MW||69069 Da|
|Other Names||Afamin, Alpha-albumin, Alpha-Alb, AFM, ALB2, ALBA|
|Format||0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||Afamin / alpha Albumin Antibody (internal region) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Vitamin E binding protein. May transport vitamin E in body fluids under conditions where the lipoprotein system is not sufficient. May be involved in the regulation and transport of vitamin E at the blood-brain barrier.|
|Tissue Location||High level detected in plasma but also in extravascular fluids such as follicular and cerebrospinal fluids (at protein level).|
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Provided below are standard protocols that you may find useful for product applications.
Afamin is synthesized by cerebrovascular endothelial cells and mediates alpha-tocopherol transport across an in vitro model of the blood-brain barrier. Kratzer I, Bernhart E, Wintersperger A, Hammer A, Waltl S, Malle E, Sperk G, Wietzorrek G, Dieplinger H, Sattler W. Journal of neurochemistry 2009 Feb 108 (3): 707-18. PMID: 19046407
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