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Pleiotrophin / PTN Antibody (internal region, near C-Term)

Peptide-affinity purified goat antibody

  • WB - Pleiotrophin / PTN Antibody (internal region, near C-Term) AF3007a
    AF3007a (0.3 µg/ml) staining of Rat Brain lysate (35 µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P21246
Other Accession NP_002816.1, 5764, 19242 (mouse), 24924 (rat)
Reactivity Human
Predicted Mouse, Rat, Pig, Dog, Cow
Host Goat
Clonality Polyclonal
Concentration 0.5 mg/ml
Isotype IgG
Calculated MW 18942 Da
Additional Information
Gene ID 5764
Other Names Pleiotrophin, PTN, Heparin-binding brain mitogen, HBBM, Heparin-binding growth factor 8, HBGF-8, Heparin-binding growth-associated molecule, HB-GAM, Heparin-binding neurite outgrowth-promoting factor 1, HBNF-1, Osteoblast-specific factor 1, OSF-1, PTN, HBNF1, NEGF1
Format 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsPleiotrophin / PTN Antibody (internal region, near C-Term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name PTN
Synonyms HBNF1, NEGF1
Function Secreted growth factor that induces neurite outgrowth and which is mitogenic for fibroblasts, epithelial, and endothelial cells. Binds anaplastic lymphoma kinase (ALK) which induces MAPK pathway activation, an important step in the anti- apoptotic signaling of PTN and regulation of cell proliferation.
Cellular Location Secreted.
Tissue Location Osteoblast and brain.
Research Areas
Citations (0)

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Genomic organization of the human HBNF gene and characterization of an HBNF variant protein as a splice mutant Kretschmer PJ, Fairhurst JL, Hulmes JD, Popjes ML, Böhlen P, Kovesdi I Biochem Biophys Res Commun. 1993 Apr 30;192(2):420-9. PMID: 8484754

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$ 325.00
Cat# AF3007a
(40 western blots)
Availability: 7-10 days
Bulk Size
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