|Application ||WB, E|
|Other Accession||NP_004783.2, 9360, 228005 (mouse), 83624 (rat)|
|Predicted||Mouse, Rat, Dog, Cow|
|Calculated MW||88617 Da|
|Other Names||Peptidyl-prolyl cis-trans isomerase G, PPIase G, Peptidyl-prolyl isomerase G, 220.127.116.11, CASP10, Clk-associating RS-cyclophilin, CARS-Cyp, CARS-cyclophilin, SR-cyclophilin, SR-cyp, SRcyp, Cyclophilin G, Rotamase G, PPIG|
|Format||0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||PPIG Antibody (internal region) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. May be implicated in the folding, transport, and assembly of proteins. May play an important role in the regulation of pre-mRNA splicing.|
|Cellular Location||Nucleus matrix. Nucleus speckle. Note=Colocalizes with RNA splicing factors at nuclear speckles|
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A common variant in DRD3 receptor is associated with autism spectrum disorder. de Krom M, Staal WG, Ophoff RA, Hendriks J, Buitelaar J, Franke B, de Jonge MV, Bolton P, Collier D, Curran S, van Engeland H, van Ree JM. Biological psychiatry 2009 Apr 65 (7): 625-30. PMID: 19058789
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