|Application ||WB, E|
|Other Accession||NP_055210.2, 27071|
|Calculated MW||32194 Da|
|Other Names||Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3-phosphoinositide, hDAPP1, B lymphocyte adapter protein Bam32, B-cell adapter molecule of 32 kDa, DAPP1, BAM32|
|Format||0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||DAPP1 / BAM32 Antibody (internal region, near C-Term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||May act as a B-cell-associated adapter that regulates B- cell antigen receptor (BCR)-signaling downstream of PI3K.|
|Cellular Location||Cytoplasm. Membrane; Peripheral membrane protein. Note=Membrane-associated after cell stimulation leading to its translocation|
|Tissue Location||Highly expressed in placenta and lung, followed by brain, heart, kidney, liver, pancreas and skeletal muscle. Expressed by B-lymphocytes, but not T-lymphocytes or nonhematopoietic cells.|
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Provided below are standard protocols that you may find useful for product applications.
The B lymphocyte adaptor molecule of 32 kilodaltons (Bam32) regulates B cell antigen receptor internalization. Niiro H, Allam A, Stoddart A, Brodsky FM, Marshall AJ, Clark EA, Journal of immunology (Baltimore, Md. : 1950) 2004 Nov 173 (9): 5601-9. PMID: 15494510
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