|Application ||WB, E|
|Other Accession||NP_115731.2, NP_001135973.1, 84315, 72825 (mouse), 315999 (rat)|
|Reactivity||Human, Mouse, Rat|
|Calculated MW||62131 Da|
|Other Names||Vacuolar fusion protein MON1 homolog A, MON1A, SAND1|
|Format||0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||MON1A (aa478-489) Antibody (internal region) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Plays an important role in membrane trafficking through the secretory apparatus. Not involved in endocytic trafficking to lysosomes (By similarity). Acts in concert with CCZ1, as a guanine exchange factor (GEF) for RAB7, promotes the exchange of GDP to GTP, converting it from an inactive GDP-bound form into an active GTP-bound form (PubMed:23084991).|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
This antibody is expected to recognize isoforms a and b (NP_115731.2; NP_001135973.1). Amino acid numbering in name refers to sequence NP_115731.2.
A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration. Lim J, Hao T, Shaw C, Patel AJ, Szabó G, Rual JF, Fisk CJ, Li N, Smolyar A, Hill DE, Barabási AL, Vidal M, Zoghbi HY. Cell 2006 May 125 (4): 801-14. PMID: 16713569
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