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MON1A (aa478-489) Antibody (internal region)

Peptide-affinity purified goat antibody

     
  • WB - MON1A (aa478-489) Antibody (internal region) AF3113a
    AF3113a (1 µg/ml) staining of Human Pancreas lysate (35 µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession Q86VX9
Other Accession NP_115731.2, NP_001135973.1, 84315, 72825 (mouse), 315999 (rat)
Reactivity Human, Mouse, Rat
Predicted Dog, Cow
Host Goat
Clonality Polyclonal
Concentration 0.5 mg/ml
Isotype IgG
Calculated MW 62131 Da
Additional Information
Gene ID 84315
Other Names Vacuolar fusion protein MON1 homolog A, MON1A, SAND1
Format 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsMON1A (aa478-489) Antibody (internal region) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name MON1A
Synonyms SAND1
Function Plays an important role in membrane trafficking through the secretory apparatus. Not involved in endocytic trafficking to lysosomes (By similarity). Acts in concert with CCZ1, as a guanine exchange factor (GEF) for RAB7, promotes the exchange of GDP to GTP, converting it from an inactive GDP-bound form into an active GTP-bound form (PubMed:23084991).
Research Areas
Citations (0)

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Background

This antibody is expected to recognize isoforms a and b (NP_115731.2; NP_001135973.1). Amino acid numbering in name refers to sequence NP_115731.2.

References

A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration. Lim J, Hao T, Shaw C, Patel AJ, Szabó G, Rual JF, Fisk CJ, Li N, Smolyar A, Hill DE, Barabási AL, Vidal M, Zoghbi HY. Cell 2006 May 125 (4): 801-14. PMID: 16713569

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$ 335.00
Cat# AF3113a
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