|Other Accession||NP_116244.1, 84941|
|Calculated MW||39002 Da|
|Other Names||Hematopoietic SH2 domain-containing protein, Hematopoietic SH2 protein, Adaptor in lymphocytes of unknown function X, HSH2D, ALX|
|Format||0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||HSH2D (aa325-339) Antibody (internal region) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||May be a modulator of the apoptotic response through its ability to affect mitochondrial stability (By similarity). Adapter protein involved in tyrosine kinase and CD28 signaling. Seems to affect CD28-mediated activation of the RE/AP element of the interleukin-2 promoter.|
|Cellular Location||Cytoplasm. Nucleus.|
|Tissue Location||Predominantly expressed in spleen and hematopoietic cells such as peripheral blood leukocytes and weakly expressed in prostate, thymus, heart, small intestine and placenta.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
email@example.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
The carboxyl-terminal segment of the adaptor protein ALX directs its nuclear export during T cell activation. Shapiro MJ, Chen YY, Shapiro VS, The Journal of biological chemistry 2005 Nov 280 (46): 38242-6. PMID: 16169852
If you have used an Abgent product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at firstname.lastname@example.org.