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ZGLP1 Antibody (internal region)
Peptide-affinity purified goat antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| E |
|---|---|
| Primary Accession | P0C6A0 |
| Other Accession | NP_001096637.1, 100125288, 100009600 (mouse) |
| Predicted | Human, Mouse, Cow |
| Host | Goat |
| Clonality | Polyclonal |
| Concentration | 0.5 mg/ml |
| Isotype | IgG |
| Calculated MW | 29628 Da |
| Gene ID | 100125288 |
|---|---|
| Other Names | GATA-type zinc finger protein 1, GATA-like protein 1, GLP-1, ZGLP1, GLP1 |
| Format | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | ZGLP1 Antibody (internal region) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | ZGLP1 (HGNC:37245) |
|---|---|
| Function | Transcriptional regulator that plays a key role in germ cell development. Determines the oogenic fate by activating key genes for the oogenic program and meiotic prophase entry. Acts downstream of bone morphogenetic protein (BMP) by regulating expression of genes required for the oogenic programs, which are repressed by Polycomb activities in sexually uncommitted germ cells. Regulates expression of STRA8, a central downstream effector for the meiotic program. Acts independently of retinoic acid (RA). In males, not required for germ-cell sex determination, but required to allow the spermatogonia to efficiently accomplish the meiotic prophase. |
| Cellular Location | Nucleus {ECO:0000250|UniProtKB:Q1WG82}. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
References
GLP-1: a novel zinc finger protein required in somatic cells of the gonad for germ cell development. Li S, Lu MM, Zhou D, Hammes SR, Morrisey EE, Developmental biology 2007 Jan 301 (1): 106-16. PMID: 16982049
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