|Other Accession||NP_076955.1, 79016, 66498 (mouse)|
|Predicted||Human, Mouse, Dog|
|Calculated MW||11835 Da|
|Other Names||DET1- and DDB1-associated protein 1, Placenta cross-immune reaction antigen 1, PCIA-1, DDA1, C19orf58, PCIA1|
|Format||0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||DDA1 (aa32-42) Antibody (internal region) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||May be involved in ubiquitination and subsequent proteasomal degradation of target proteins. Component of the DDD- E2 complexes which may provide a platform for interaction with CUL4A and WD repeat proteins.|
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Provided below are standard protocols that you may find useful for product applications.
An interaction network of the mammalian COP9 signalosome identifies Dda1 as a core subunit of multiple Cul4-based E3 ligases. Olma MH, Roy M, Le Bihan T, Sumara I, Maerki S, Larsen B, Quadroni M, Peter M, Tyers M, Pintard L, J Cell Sci. 2009 Apr 1;122(Pt 7):1035-44. PMID: 19295130
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