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GNAS Antibody (internal region)

Peptide-affinity purified goat antibody

  • WB - GNAS Antibody (internal region) AF3217a
    AF3217a (1 µg/ml) staining of Jurkat lysate (35 µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
  • WB - GNAS Antibody (internal region) AF3217a
    AF3217a (0.1 µg/ml) staining of Mouse Brain (Lane 1) and Rat Brain (lane 2) lysates (35 µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P84996
Other Accession NP_000507.1, NP_001070956.1, NP_001070957.1, 2778, 14683 (mouse), 24896 (rat)
Reactivity Human, Mouse, Rat
Predicted Cow
Host Goat
Clonality Polyclonal
Concentration 0.5 mg/ml
Isotype IgG
Calculated MW 67948 Da
Additional Information
Gene ID 2778
Other Names Protein ALEX, Alternative gene product encoded by XL-exon, GNAS (HGNC:4392)
Format 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsGNAS Antibody (internal region) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name GNAS (HGNC:4392)
Function May inhibit the adenylyl cyclase-stimulating activity of guanine nucleotide-binding protein G(s) subunit alpha which is produced from the same locus in a different open reading frame.
Cellular Location Cell membrane; Peripheral membrane protein. Cell projection, ruffle. Note=Predominantly associated with cell membrane ruffles.
Research Areas
Citations (0)

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This antibody is expected to recognize all three reported isoforms NP_000507.1, NP_001070956.1 and NP_536350.2. However, in Mouse it is expected to recognize reporterd isoforms GNASL (NP_963910.1) and XLas (NP_034439.2) only.


Prevalence of TSH receptor and Gsalpha mutations in 45 autonomously functioning thyroid nodules in Japan. Nishihara E, Amino N, Maekawa K, Yoshida H, Ito M, Kubota S, Fukata S, Miyauchi A, Endocrine journal 2009 Dec 56 (6): 791-8. PMID: 19550078

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$ 325.00
Cat# AF3217a
(40 western blots)
Availability: 7-10 days
Bulk Size
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