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IL12RB1 Antibody (internal region)

Peptide-affinity purified goat antibody

  • WB - IL12RB1 Antibody (internal region) AF3227a
    AF3227a (0.3 µg/ml) staining of Peripharal Blood Lymphocytes lysate (35 µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P42701
Other Accession NP_005526.1, 3594
Reactivity Human
Host Goat
Clonality Polyclonal
Concentration 0.5 mg/ml
Isotype IgG
Calculated MW 73109 Da
Additional Information
Gene ID 3594
Other Names Interleukin-12 receptor subunit beta-1, IL-12 receptor subunit beta-1, IL-12R subunit beta-1, IL-12R-beta-1, IL-12RB1, IL-12 receptor beta component, CD212, IL12RB1, IL12R, IL12RB
Format 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsIL12RB1 Antibody (internal region) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name IL12RB1
Synonyms IL12R, IL12RB
Function Functions as an interleukin receptor which binds interleukin-12 with low affinity and is involved in IL12 transduction. Associated with IL12RB2 it forms a functional, high affinity receptor for IL12. Associates also with IL23R to form the interleukin-23 receptor which functions in IL23 signal transduction probably through activation of the Jak-Stat signaling cascade.
Cellular Location Membrane; Single-pass type I membrane protein
Research Areas
Citations (0)

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This antibody is expected to recognize isoform 1 (NP_005526.1) only.


Association of single nucleotide polymorphisms in the IL-12 (IL-12A and B) and IL-12 receptor (IL-12Rbeta1 and beta2) genes and gene-gene interactions with atopic dermatitis in Koreans. Namkung JH, Lee JE, Kim E, Kim S, Kim S, Shin ES, Cho EY, Yang JM, J Dermatol Sci. 2010 Mar;57(3):199-206. PMID: 20060272

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$ 325.00
Cat# AF3227a
(40 western blots)
Availability: 7-10 days
Bulk Size
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