|Application ||WB, E|
|Other Accession||NP_060399.1, 55670|
|Calculated MW||33898 Da|
|Other Names||Peroxisome assembly protein 26, Peroxin-26, PEX26|
|Format||0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||PEX26 Antibody (internal region) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Probably required for protein import into peroxisomes. Anchors PEX1 and PEX6 to peroxisome membranes, possibly to form heteromeric AAA ATPase complexes required for the import of proteins into peroxisomes. Involved in the import of catalase and proteins containing a PTS2 target sequence, but not in import of proteins with a PTS1 target sequence.|
|Cellular Location||Peroxisome membrane; Single-pass type II membrane protein|
|Tissue Location||Widely expressed. Highly expressed in kidney, liver, brain and skeletal muscles. Expressed at intermediate level in pancreas, placenta and heart. Weakly expressed in lung|
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Reported variants represent identical protein: NP_060399.1, NP_001121121.1
Identification of novel mutations and sequence variation in the Zellweger syndrome spectrum of peroxisome biogenesis disorders. Yik WY, Steinberg SJ, Moser AB, Moser HW, Hacia JG, Human mutation 2009 Mar 30 (3): E467-80. PMID: 19105186
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