|Other Accession||NP_003768.2, 8701, 13411 (mouse)|
|Predicted||Human, Mouse, Rabbit, Dog, Cow|
|Calculated MW||520369 Da|
|Other Names||Dynein heavy chain 11, axonemal, Axonemal beta dynein heavy chain 11, Ciliary dynein heavy chain 11, DNAH11|
|Format||0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||DNAH11 (aa 693-704) Antibody (internal region) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Force generating protein of respiratory cilia. Produces force towards the minus ends of microtubules. Dynein has ATPase activity; the force-producing power stroke is thought to occur on release of ADP.|
|Cellular Location||Cytoplasm, cytoskeleton, cilium axoneme.|
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Provided below are standard protocols that you may find useful for product applications.
Ciliary defects and genetics of primary ciliary dyskinesia. Escudier E, Duquesnoy P, Papon JF, Amselem S, Paediatric respiratory reviews 2009 Jun 10 (2): 51-4. PMID: 19410201
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