|Other Accession||NP_003768.2, 8701, 13411 (mouse)|
|Predicted||Human, Mouse, Rabbit, Dog, Cow|
|Calculated MW||520369 Da|
|Other Names||Dynein heavy chain 11, axonemal, Axonemal beta dynein heavy chain 11, Ciliary dynein heavy chain 11, DNAH11|
|Format||0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||DNAH11 (aa 693-704) Antibody (internal region) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Force generating protein of respiratory cilia. Produces force towards the minus ends of microtubules. Dynein has ATPase activity; the force-producing power stroke is thought to occur on release of ADP.|
|Cellular Location||Cytoplasm, cytoskeleton, cilium axoneme.|
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Ciliary defects and genetics of primary ciliary dyskinesia. Escudier E, Duquesnoy P, Papon JF, Amselem S, Paediatric respiratory reviews 2009 Jun 10 (2): 51-4. PMID: 19410201
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