|Application ||WB, E|
|Other Accession||NP_000071.1, 1145, 11448 (mouse), 29422 (rat)|
|Predicted||Human, Rat, Cow|
|Calculated MW||54697 Da|
|Other Names||Acetylcholine receptor subunit epsilon, CHRNE, ACHRE|
|Format||0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||ACHRE / CHRNE Antibody (Internal region) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane.|
|Cellular Location||Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
AChR deficiency due to epsilon-subunit mutations: two common mutations in the Netherlands. Faber CG, Molenaar PC, Vles JS, Bonifati DM, Verschuuren JJ, van Doorn PA, Kuks JB, Wokke JH, Beeson D, De Baets M, Journal of neurology 2009 Oct 256 (10): 1719-23. PMID: 19544078
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