|Application ||WB, E|
|Other Accession||NP_619635.1, 116444|
|Calculated MW||112992 Da|
|Other Names||Glutamate receptor ionotropic, NMDA 3B, GluN3B, N-methyl-D-aspartate receptor subtype 3B, NMDAR3B, NR3B, GRIN3B|
|Format||0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||GRIN3B Antibody (C-Term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||NMDA receptor subtype of glutamate-gated ion channels with reduced single-channel conductance, low calcium permeability and low voltage-dependent sensitivity to magnesium. Mediated by glycine.|
|Cellular Location||Cell membrane; Multi-pass membrane protein. Cell junction, synapse, postsynaptic cell membrane. Note=Requires the presence of GRIN1 to be targeted at the plasma membrane|
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Pharmacogenetics of antipsychotic response in the CATIE trial: a candidate gene analysis. Need AC, Keefe RS, Ge D, Grossman I, Dickson S, McEvoy JP, Goldstein DB, European journal of human genetics : EJHG 2009 Jul 17 (7): 946-57. PMID: 19156168
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