|Application ||IHC, E|
|Other Accession||NP_004732.2, 9221, 70769 (mouse), 64896 (rat)|
|Predicted||Mouse, Rat, Dog, Cow|
|Calculated MW||73603 Da|
|Other Names||Nucleolar and coiled-body phosphoprotein 1, 140 kDa nucleolar phosphoprotein, Nopp140, Hepatitis C virus NS5A-transactivated protein 13, HCV NS5A-transactivated protein 13, Nucleolar 130 kDa protein, Nucleolar phosphoprotein p130, NOLC1, KIAA0035, NS5ATP13|
|Format||0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||NOLC1 Antibody (internal region) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Related to nucleologenesis, may play a role in the maintenance of the fundamental structure of the fibrillar center and dense fibrillar component in the nucleolus. It has intrinsic GTPase and ATPase activities. May play an important role in transcription catalyzed by RNA polymerase I.|
|Cellular Location||Nucleus, nucleolus. Cytoplasm. Note=Shuttles between the nucleolus and the cytoplasm. At telophase it begins to assemble into granular-like pre-nucleolar bodies which are subsequently relocated to nucleoli at the early G1-phase|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Localization of Nopp140 within mammalian cells during interphase and mitosis. Thiry M, Cheutin T, Lamaye F, Thelen N, Meier UT, O'Donohue MF, Ploton D, Histochemistry and cell biology 2009 Aug 132 (2): 129-40. PMID: 19381672
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