|Other Accession||NP_006166.3, NP_932326.2, 4892, 18175 (mouse), 307982 (rat)|
|Predicted||Human, Mouse, Rat, Pig, Dog, Cow|
|Calculated MW||197074 Da|
|Other Names||Nebulin-related-anchoring protein, N-RAP, NRAP (HGNC:7988)|
|Format||0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||NRAP Antibody (internal region) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||May be involved in anchoring the terminal actin filaments in the myofibril to the membrane and in transmitting tension from the myofibrils to the extracellular matrix.|
|Cellular Location||Note=Localized at the myotendinous junction in skeletal muscle and at the intercalated disk in cardiac muscle|
|Tissue Location||Expressed in cardiac and skeletal muscle.|
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Provided below are standard protocols that you may find useful for product applications.
This antibody is expected to recognize both reported isoforms (NP_006166.3; NP_932326.2).
Genomic organization, alternative splicing, and expression of human and mouse N-RAP, a nebulin-related LIM protein of striated muscle. Mohiddin SA, Lu S, Cardoso JP, Carroll S, Jha S, Horowits R, Fananapazir L, Cell motility and the cytoskeleton 2003 Jul 55 (3): 200-12. PMID: 12789664
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