|Application ||WB, E|
|Other Accession||NP_733936.1, NP_001071.1, 7915, 214579 (mouse), 291133 (rat)|
|Reactivity||Human, Mouse, Rat|
|Calculated MW||57215 Da|
|Other Names||Succinate-semialdehyde dehydrogenase, mitochondrial, 220.127.116.11, Aldehyde dehydrogenase family 5 member A1, NAD(+)-dependent succinic semialdehyde dehydrogenase, ALDH5A1, SSADH|
|Format||0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||ALDH5A1 (aa 301-312) Antibody (internal region) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Catalyzes one step in the degradation of the inhibitory neurotransmitter gamma-aminobutyric acid (GABA).|
|Tissue Location||Brain, pancreas, heart, liver, skeletal muscle and kidney. Lower in placenta|
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Provided below are standard protocols that you may find useful for product applications.
This antibody is expected to recognize both reported isoforms (NP_733936.1; NP_001071.1). Amino acid numbering in name calculated from NP_733936.1.
Human variation in alcohol response is influenced by variation in neuronal signaling genes. Joslyn G, Ravindranathan A, Brush G, Schuckit M, White RL, Alcoholism, clinical and experimental research 2010 May 34 (5): 800-12. PMID: 20201926
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