|Application ||WB, E|
|Other Accession||NP_079434.3, NP_001035541.1, 80230, 216724 (mouse), 360521 (rat)|
|Predicted||Mouse, Rat, Dog, Cow|
|Calculated MW||79818 Da|
|Other Names||RUN and FYVE domain-containing protein 1, FYVE-finger protein EIP1, La-binding protein 1, Rab4-interacting protein, Zinc finger FYVE domain-containing protein 12, RUFY1, RABIP4, ZFYVE12|
|Format||0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||RUFY1 Antibody (internal region) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Binds phospholipid vesicles containing phosphatidylinositol 3-phosphate and participates in early endosomal trafficking.|
|Cellular Location||Cytoplasm. Early endosome membrane; Peripheral membrane protein|
|Tissue Location||Broadly expressed, with highest levels in lung, testis, kidney and brain.|
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Provided below are standard protocols that you may find useful for product applications.
This antibody is expected to recognize both reported isoforms (NP_079434.3; NP_001035541.1). Reported variants represent identical protein: NP_001035542.1, NP_001035541.1.
ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage. Matsuoka S, Ballif BA, Smogorzewska A, McDonald ER, Hurov KE, Luo J, Bakalarski CE, Zhao Z, Solimini N, Lerenthal Y, Shiloh Y, Gygi SP, Elledge SJ, Science (New York, N.Y.) 2007 May 316 (5828): 1160-6. PMID: 17525332
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