|Application ||WB, E|
|Other Accession||NP_849195.2, 266743, 225872 (mouse), 266734 (rat)|
|Reactivity||Human, Mouse, Rat|
|Calculated MW||87117 Da|
|Other Names||Neuronal PAS domain-containing protein 4, Neuronal PAS4, Class E basic helix-loop-helix protein 79, bHLHe79, HLH-PAS transcription factor NXF, PAS domain-containing protein 10, NPAS4, BHLHE79, NXF, PASD10|
|Format||0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||NPAS4 Antibody (internal region) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Synonyms||BHLHE79, NXF, PASD10|
|Function||Acts as a transcriptional activator in the presence of ARNT. Can activate the CME (CNS midline enhancer) element and the expression of the drebrin gene.|
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Provided below are standard protocols that you may find useful for product applications.
Identification of a novel basic helix-loop-helix-PAS factor, NXF, reveals a Sim2 competitive, positive regulatory role in dendritic-cytoskeleton modulator drebrin gene expression. Ooe N, Saito K, Mikami N, Nakatuka I, Kaneko H, Molecular and cellular biology 2004 Jan 24 (2): 608-16. PMID: 14701734
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