|Application ||WB, E|
|Other Accession||NP_849195.2, 266743, 225872 (mouse), 266734 (rat)|
|Reactivity||Human, Mouse, Rat|
|Calculated MW||87117 Da|
|Other Names||Neuronal PAS domain-containing protein 4, Neuronal PAS4, Class E basic helix-loop-helix protein 79, bHLHe79, HLH-PAS transcription factor NXF, PAS domain-containing protein 10, NPAS4, BHLHE79, NXF, PASD10|
|Format||0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||NPAS4 Antibody (internal region) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Synonyms||BHLHE79, NXF, PASD10|
|Function||Acts as a transcriptional activator in the presence of ARNT. Can activate the CME (CNS midline enhancer) element and the expression of the drebrin gene.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Identification of a novel basic helix-loop-helix-PAS factor, NXF, reveals a Sim2 competitive, positive regulatory role in dendritic-cytoskeleton modulator drebrin gene expression. Ooe N, Saito K, Mikami N, Nakatuka I, Kaneko H, Molecular and cellular biology 2004 Jan 24 (2): 608-16. PMID: 14701734
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