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POLDIP2 Antibody (internal region)

Peptide-affinity purified goat antibody

     
  • WB - POLDIP2 Antibody (internal region) AF3419a
    AF3419a (1 µg/ml) staining of K562 (A), MCF7 (B) and Mouse Liver (C) lysates (35 µg protein in RIPA buffer). Primary incubation was overnight at 4C. Detected by chemiluminescence.
  • WB - POLDIP2 Antibody (internal region) AF3419a
    AF3419a (0.5 µg/ml) staining of Rat VSMC lysate (35 µg protein in RIPA buffer). Primary incubation was overnight at 4C. Detected by chemiluminescence. Data provided by Everest Grant winner Dr. B. Lassegue, Emory University, Atlanta, USA
  • WB - POLDIP2 Antibody (internal region) AF3419a
    AF3419a (2 µg/ml) staining of Mouse Liver lysate (35 µg protein in RIPA buffer). Primary incubation was overnight at 4C. Detected by chemiluminescence.
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession Q9Y2S7
Other Accession NP_056399.1, 26073, 67811 (mouse)
Reactivity Human, Mouse, Rat
Predicted Dog, Cow
Host Goat
Clonality Polyclonal
Concentration 0.5 mg/ml
Isotype IgG
Additional Information
Other Names Polymerase delta-interacting protein 2, 38 kDa DNA polymerase delta interaction protein, p38, POLDIP2, PDIP38, POLD4
Format 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsPOLDIP2 Antibody (internal region) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name POLDIP2
Synonyms PDIP38, POLD4
Cellular Location Nucleus. EMBL; AF179891; AAK92018.1; -; mRNA EMBL; AF077203; AAD26998.1; -; mRNA EMBL; AK313232; BAG36043.1; -; mRNA EMBL; BC000655; AAH00655.1; -; mRNA EMBL; BC009265; AAH09265.1; -; mRNA CCDS; CCDS74018.1; - RefSeq; NP_001277074.1; NM_001290145.1 RefSeq; NP_056399.1; NM_015584.4 UniGene; Hs.241543; - ProteinModelPortal; Q9Y2S7; - SMR; Q9Y2S7; - BioGrid; 117531; 68 IntAct; Q9Y2S7; 40 MINT; Q9Y2S7; - iPTMnet; Q9Y2S7; - PhosphoSitePlus; Q9Y2S7; - BioMuta; POLDIP2; - EPD; Q9Y2S7; - MaxQB; Q9Y2S7; - PeptideAtlas; Q9Y2S7; - PRIDE; Q9Y2S7; - ProteomicsDB; 85887; - DNASU; 26073; - Ensembl; ENST00000540200; ENSP00000475924; ENSG00000004142 GeneID; 26073; - KEGG; hsa:26073; - UCSC; uc032ezc.2; human CTD; 26073; - DisGeNET; 26073; - EuPathDB; HostDB:ENSG00000004142.11; - GeneCards; POLDIP2; - HGNC; HGNC:23781; POLDIP2 HPA; HPA007700; - MIM; 611519; gene neXtProt; NX_Q9Y2S7; - OpenTargets; ENSG00000004142; - PharmGKB; PA134866227; - GeneTree; ENSGT00390000010198; - HOVERGEN; HBG053549; - InParanoid; Q9Y2S7; - KO; K17809; - OMA; THTFYQV; - OrthoDB; EOG091G0BNI; - PhylomeDB; Q9Y2S7; - ChiTaRS; POLDIP2; human GeneWiki; POLDIP2; - GenomeRNAi; 26073; - PRO; PR:Q9Y2S7; - Proteomes; UP000005640; Chromosome 17 Bgee; ENSG00000004142; - CleanEx; HS_POLD4; - CleanEx; HS_POLDIP2; - ExpressionAtlas; Q9Y2S7; baseline and differential Genevisible; Q9Y2S7; HS GO; GO:0042645; C:mitochondrial nucleoid; IDA:BHF-UCL GO; GO:0005739; C:mitochondrion; IDA:LIFEdb GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell GO; GO:0003677; F:DNA binding; IEA:InterPro GO; GO:0070584; P:mitochondrion morphogenesis; IEA:Ensembl GO; GO:0016242; P:negative regulation of macroautophagy; IEA:Ensembl GO; GO:0045931; P:positive regulation of mitotic cell cycle; IEA:Ensembl Gene3D; 2.60.40.1470; -; 1 InterPro; IPR007474; ApaG_domain InterPro; IPR036767; ApaG_sf InterPro; IPR011722; Hemimethylated_DNA-bd_dom InterPro; IPR036623; Hemimethylated_DNA-bd_sf Pfam; PF04379; DUF525; 1 Pfam; PF08755; YccV-like; 1 SMART; SM00992; YccV-like; 1 SUPFAM; SSF110069; SSF110069; 1 SUPFAM; SSF141255; SSF141255; 2 PROSITE; PS51087; APAG; 1 1: Evidence at protein level; Complete proteome; Nucleus; Phosphoprotein; Reference proteome CHAIN 1 368 Polymerase delta-interacting protein 2 /FTId=PRO_0000197975 DOMAIN 235 360 ApaG. {ECO:0000255|PROSITE- ProRule:PRU00412} MOD_RES 292 292 Phosphothreonine CONFLICT 9 9 A -> P (in Ref. 1; AAK92018) CONFLICT 28 28 R -> K (in Ref. 1; AAK92018) SEQUENCE 368 AA; 42033 MW; 1882F93273542CCF CRC64; MAACTARRAL AVGSRWWSRS LTGARWPRPL CAAAGAGAFS PASTTTTRRH LSSRNRPEGK VLETVGVFEV PKQNGKYETG QLFLHSIFGY RGVVLFPWQA RLYDRDVASA APEKAENPAG HGSKEVKGKT HTYYQVLIDA RDCPHISQRS QTEAVTFLAN HDDSRALYAI PGLDYVSHED ILPYTSTDQV PIQHELFERF LLYDQTKAPP FVARETLRAW QEKNHPWLEL SDVHRETTEN IRVTVIPFYM GMREAQNSHV YWWRYCIRLE NLDSDVVQLR ERHWRIFSLS GTLETVRGRG VVGREPVLSK EQPAFQYSSH VSLQASSGHM WGTFRFERPD GSHFDVRIPP FSLESNKDEK TPPSGLHW
Research Areas
Citations (0)

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References

Complex sense-antisense architecture of TNFAIP1/POLDIP2 on 17q11.2 represents a novel transcriptional structural-functional gene module involved in breast cancer progression. Grinchuk OV, Motakis E, Kuznetsov VA, BMC genomics 2010 11 Suppl 1 : S9. PMID: 20158880

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$ 335.00
Cat# AF3419a
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