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Ascl3 (mouse) Antibody (internal region)
Peptide-affinity purified goat antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | Q9NQ33 |
| Other Accession | NP_064435.1, 56676, 56787 (mouse) |
| Reactivity | Human, Mouse |
| Predicted | Cow |
| Host | Goat |
| Clonality | Polyclonal |
| Concentration | 0.5 mg/ml |
| Isotype | IgG |
| Calculated MW | 20928 Da |
| Gene ID | 56676 |
|---|---|
| Other Names | Achaete-scute homolog 3, ASH-3, hASH3, Class A basic helix-loop-helix protein 42, bHLHa42, bHLH transcriptional regulator Sgn-1, ASCL3, BHLHA42, HASH3, SGN1 |
| Format | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | Ascl3 (mouse) Antibody (internal region) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | ASCL3 (HGNC:740) |
|---|---|
| Synonyms | BHLHA42, HASH3, SGN1 |
| Function | Transcriptional repressor. Inhibits myogenesis. Plays a role in progenitor cells which differentiate into ductal and acinar, but not myoepithelial, cell lineages in the salivary glands. Involved in the functions of the microvillar cells and Bowman's glands and probably, in a non-cell-autonomous manner, in the development or regeneration of a complete olfactory epithelium (OE). |
| Cellular Location | Nucleus. |
| Tissue Location | Widely expressed in fetal and adult tissues. |
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Provided below are standard protocols that you may find useful for product applications.
References
Ascl3 expression marks a progenitor population of both acinar and ductal cells in mouse salivary glands. Bullard T, Koek L, Roztocil E, Kingsley PD, Mirels L, Ovitt CE, Developmental biology 2008 Aug 320 (1): 72-8. PMID: 18572159
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