|Application ||WB, E|
|Other Accession||NP_005836.2, NP_001098985.1, 10257|
|Calculated MW||149527 Da|
|Other Names||Multidrug resistance-associated protein 4, ATP-binding cassette sub-family C member 4, MRP/cMOAT-related ABC transporter, Multi-specific organic anion transporter B, MOAT-B, ABCC4, MRP4|
|Format||0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||ABCC4 (aa70-82) Antibody (N-Term, near) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||May be an organic anion pump relevant to cellular detoxification.|
|Cellular Location||Membrane; Multi-pass membrane protein.|
|Tissue Location||Widely expressed, with particularly high levels in prostate, but is barely detectable in liver|
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Provided below are standard protocols that you may find useful for product applications.
This antibody is expected to recognize both reported isoforms (NP_005836.2; NP_001098985.1).
Aryl hydrocarbon receptor and NF-E2-related factor 2 are key regulators of human MRP4 expression. Xu S, Weerachayaphorn J, Cai SY, Soroka CJ, Boyer JL, American journal of physiology. Gastrointestinal and liver physiology 2010 Jul 299 (1): G126-35. PMID: 20395535
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