|Application ||WB, IHC, E|
|Other Accession||NP_000328.2, NP_758447.1, NP_001121681.1, 6444, 24052 (mouse), 497892 (rat)|
|Predicted||Mouse, Pig, Dog, Cow|
|Calculated MW||32071 Da|
|Other Names||Delta-sarcoglycan, Delta-SG, 35 kDa dystrophin-associated glycoprotein, 35DAG, SGCD|
|Format||0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||Delta-Sarcoglycan (aa245-257) Antibody (internal region) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Component of the sarcoglycan complex, a subcomplex of the dystrophin-glycoprotein complex which forms a link between the F-actin cytoskeleton and the extracellular matrix.|
|Cellular Location||Cell membrane, sarcolemma; Single-pass type II membrane protein. Cytoplasm, cytoskeleton|
|Tissue Location||Most strongly expressed in skeletal and cardiac muscle. Also detected in smooth muscle. Weak expression in brain and lung|
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Provided below are standard protocols that you may find useful for product applications.
This antibody is expected to recognize isoform 1 (NP_000328.2) and isoform 3 (NP_001121681.1).
Expression of the dystrophin-glycoprotein complex is a marker for human airway smooth muscle phenotype maturation. Sharma P, Tran T, Stelmack GL, McNeill K, Gosens R, Mutawe MM, Unruh H, Gerthoffer WT, Halayko AJ, American journal of physiology. Lung cellular and molecular physiology 2008 Jan 294 (1): L57-68. PMID: 17993586
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