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>   home   >   Products   >   Primary Antibodies   >   Antibody Collections   >   Goat Antibodies   >   Scn10a / Nav1.8 (mouse) Antibody (internal region)   

Scn10a / Nav1.8 (mouse) Antibody (internal region)

Peptide-affinity purified goat antibody

Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9Y5Y9
Other Accession NP_033160.2, 6336, 20264 (mouse), 29571 (rat)
Predicted Mouse, Rat
Host Goat
Clonality Polyclonal
Concentration 0.5 mg/ml
Isotype IgG
Calculated MW 220626 Da
Additional Information
Gene ID 6336
Other Names Sodium channel protein type 10 subunit alpha, Peripheral nerve sodium channel 3, PN3, hPN3, Sodium channel protein type X subunit alpha, Voltage-gated sodium channel subunit alpha Nav1.8, SCN10A
Format 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsScn10a / Nav1.8 (mouse) Antibody (internal region) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name SCN10A
Function Tetrodotoxin-resistant channel that mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium- selective channel through which sodium ions may pass in accordance with their electrochemical gradient. Plays a role in neuropathic pain mechanisms.
Cellular Location Membrane; Multi-pass membrane protein. Note=It can be translocated to the extracellular membrane through association with S100A10
Tissue Location Expressed in the dorsal root ganglia and sciatic nerve.
Research Areas
Citations (0)

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Transmembrane segments prevent surface expression of sodium channel Nav1.8 and promote calnexin-dependent channel degradation. Li Q, Su YY, Wang H, Li L, Wang Q, Bao L, The Journal of biological chemistry 2010 Oct 285 (43): 32977-87. PMID: 20720009

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$ 325.00
Cat# AF3512a
(40 western blots)
Availability: 7-10 days
Bulk Size
Seasonal Special on Bulk Order
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