|Application ||WB, E|
|Other Accession||NP_056998.4, 51061|
|Calculated MW||110529 Da|
|Other Names||Thioredoxin domain-containing protein 11, EF-hand-binding protein 1, TXNDC11, EFP1|
|Format||0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||TXNDC11 (aa113-126) Antibody (internal region) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||May act as a redox regulator involved in DUOX proteins folding. The interaction with DUOX1 and DUOX2 suggest that it belongs to a multiprotein complex constituting the thyroid H(2)O(2) generating system. It is however not sufficient to assist DUOX1 and DUOX2 in H(2)O(2) generation.|
|Cellular Location||Endoplasmic reticulum membrane; Single-pass membrane protein|
|Tissue Location||Widely expressed at low level. Expressed at higher level in thyroid and prostate|
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A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration. Lim J, Hao T, Shaw C, Patel AJ, Szabó G, Rual JF, Fisk CJ, Li N, Smolyar A,
Hill DE, Barabási AL, Vidal M, Zoghbi HY. Cell. 2006 May 19;125(4):801-14. PMID: 16713569
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