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>   home   >   Products   >   Primary Antibodies   >   Antibody Collections   >   Amyotrophic Lateral Sclerosis (ALS)   >   AMPA1 / GLUR1 (aa264-277) Antibody (internal region)   

AMPA1 / GLUR1 (aa264-277) Antibody (internal region)

Peptide-affinity purified goat antibody

  • WB - AMPA1 / GLUR1 (aa264-277) Antibody (internal region) AF3549a
    AF3549a (0.1 µg/ml) staining of Human Cerebellum lysate (35 µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P42261
Other Accession NP_000818.2, NP_001107655.1, 2890, 14799 (mouse), 50592 (rat)
Reactivity Human, Mouse, Rat
Predicted Dog, Cow
Host Goat
Clonality Polyclonal
Concentration 0.5 mg/ml
Isotype IgG
Calculated MW 101506 Da
Additional Information
Gene ID 2890
Other Names Glutamate receptor 1, GluR-1, AMPA-selective glutamate receptor 1, GluR-A, GluR-K1, Glutamate receptor ionotropic, AMPA 1, GluA1, GRIA1, GLUH1, GLUR1
Format 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsAMPA1 / GLUR1 (aa264-277) Antibody (internal region) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name GRIA1
Synonyms GLUH1, GLUR1
Function Ionotropic glutamate receptor. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter L- glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse. The receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist. In the presence of CACNG4 or CACNG7 or CACNG8, shows resensitization which is characterized by a delayed accumulation of current flux upon continued application of glutamate.
Cellular Location Cell membrane; Multi-pass membrane protein Endoplasmic reticulum membrane; Multi-pass membrane protein. Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein. Cell junction, synapse, postsynaptic cell membrane, postsynaptic density Cell projection, dendrite. Cell projection, dendritic spine. Note=Interaction with CACNG2, CNIH2 and CNIH3 promotes cell surface expression.
Tissue Location Widely expressed in brain.
Research Areas
Citations (0)

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This antibody is expected to recognize both reported isoforms (NP_000818.2; NP_001107655.1).


Postsynaptic receptor trafficking underlying a form of associative learning. Rumpel S, LeDoux J, Zador A, Malinow R. Science. 2005 Apr 1;308(5718):83-8. PMID: 15746389

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$ 325.00
Cat# AF3549a
(40 western blots)
Availability: 7-10 days
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