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Sirtuin 3 (mouse) Antibody (internal region)

Peptide-affinity purified goat antibody

  • WB - Sirtuin 3 (mouse) Antibody (internal region) AF3563a
    AF3563a (0.3 µg/ml) staining of Mouse Heart lysate (35 µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9NTG7
Other Accession NP_071878.2, NP_001171275.1, 23410, 64384 (mouse), 293615 (rat)
Reactivity Mouse
Predicted Human, Rat, Pig
Host Goat
Clonality Polyclonal
Concentration 0.5 mg/ml
Isotype IgG
Calculated MW 43573 Da
Additional Information
Gene ID 23410
Other Names NAD-dependent protein deacetylase sirtuin-3, mitochondrial, hSIRT3, 3.5.1.-, Regulatory protein SIR2 homolog 3, SIR2-like protein 3, SIRT3, SIR2L3
Format 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsSirtuin 3 (mouse) Antibody (internal region) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name SIRT3
Synonyms SIR2L3
Function NAD-dependent protein deacetylase. Activates or deactivates mitochondrial target proteins by deacetylating key lysine residues. Known targets include ACSS1, IDH, GDH, SOD2, PDHA1, LCAD, SDHA and the ATP synthase subunit ATP5O. Contributes to the regulation of the cellular energy metabolism. Important for regulating tissue-specific ATP levels.
Cellular Location Mitochondrion matrix
Tissue Location Widely expressed.
Research Areas
Citations (0)

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This antibody is expected to recognize both reported isoforms (NP_071878.2; NP_001171275.1). Reported variants represent identical proteins: NP_071878.2; NP_001120823.1


Sirtuin 3, a new target of PGC-1alpha, plays an important role in the suppression of ROS and mitochondrial biogenesis. Kong X, Wang R, Xue Y, Liu X, Zhang H, Chen Y, Fang F, Chang Y. PLoS One. 2010 Jul 22;5(7):e11707. PMID: 20661474

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$ 325.00
Cat# AF3563a
(40 western blots)
Availability: 7-10 days
Bulk Size
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