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Histamine Receptor H2 (aa309-323) Antibody (internal region)

Peptide-affinity purified goat antibody

  • WB - Histamine Receptor H2 (aa309-323) Antibody (internal region) AF3587a
    AF3587a (0.1 µg/ml) staining of Duodenum lysate (35 µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P25021
Other Accession NP_001124527.1, NP_071640.1, 3274
Reactivity Human
Host Goat
Clonality Polyclonal
Concentration 0.5 mg/ml
Isotype IgG
Calculated MW 40098 Da
Additional Information
Gene ID 3274
Other Names Histamine H2 receptor, H2R, HH2R, Gastric receptor I, HRH2
Format 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsHistamine Receptor H2 (aa309-323) Antibody (internal region) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name HRH2
Function The H2 subclass of histamine receptors mediates gastric acid secretion. Also appears to regulate gastrointestinal motility and intestinal secretion. Possible role in regulating cell growth and differentiation. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase and, through a separate G protein-dependent mechanism, the phosphoinositide/protein kinase (PKC) signaling pathway (By similarity).
Cellular Location Cell membrane; Multi-pass membrane protein.
Research Areas
Citations (0)

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This antibody is expected to recognize both reported isoforms (NP_001124527.1; NP_071640.1).


Histamine: its novel role as an endogenous regulator of Con A-dependent T cell proliferation. Nakane H, Sonobe Y, Watanabe T, Nakano K. Inflamm Res. 2004 Jul;53(7):324-8. PMID: 15241568

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$ 325.00
Cat# AF3587a
(40 western blots)
Availability: 7-10 days
Bulk Size
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